Small grains on the nipples during pregnancy are mainly seen in two situations: first, due to the increase in estrogen levels during pregnancy, resulting in increased secretions from the nipples and surrounding skin, which can crystallize and precipitate on the nipples if not cleaned up in time, forming fatty grains adhering to the nipples, resulting in small grains on the nipples during pregnancy. The second, after pregnancy due to progesterone increase, can cause the nipple and areola sebaceous gland hyperplasia, the formation of nodule-like elevation and projection on the skin surface, namely Montgomery gland, its physiological function is mainly through the secretion of oil lubrication nipple, keep the nipple moist and soft. The small grains of flesh on the nipples during pregnancy are a normal physiological phenomenon and do not require special treatment. It is important to pay attention to timely nipple cleaning during pregnancy to keep the nipples clean and avoid complications of infection, which can cause serious clinical consequences.