(Disclaimer: This article is for scientific purposes only. In order to protect the patient’s privacy, the relevant information in the following content has been processed.) Abstract: Sleep-wake disorders mainly include insomnia, hypersomnia, sleep-related abnormalities, and disorders of sleep-wake rhythms, which often overlap, and most of which are non-organic sleep disorders. In this case, the patient had recently experienced difficulty in falling asleep, early awakening, and nighttime dreaming, and came to the clinic due to the fear of an organic pathology. Through relevant examinations, the patient was confirmed to have sleep-wake disorder, and after medication, the patient’s insomnia symptoms were relieved and the disease gradually recovered. Basic information] Female, 25 years old [Type of disease] Sleep-wake disorder [Hospital] The Second Affiliated Hospital of Harbin Medical University [Time of consultation] January 2022 [Treatment plan] Medication (eszopiclone tablets, zolpidem tartrate tablets, bupropion capsule, venlafaxine hydrochloride capsule) [Period of treatment] Hospitalization for 5 days [Effect of treatment] Relief of insomnia symptoms and gradual recovery of the disease. Patient’s self-report: usually work, study and life stress, poor mood. Insomnia appeared one month before admission, manifesting as difficulty in falling asleep, often falling asleep 2 hours after going to bed, accompanied by early waking, waking up before 5:00 a.m., dreamy sleep at night, often nightmares, poor mental health during the day, sleepiness, palpitation, chest tightness, shortness of breath, headache, dizziness, memory loss, work and study ability to decline, self-consciousness of the head of a muddle, head swelling and pain, the patient is very disturbed by this, worrying about organic diseases, and came to my clinic. He came to our clinic for fear of organic disease. The electrocardiogram and ultrasound examination showed few premature beats and no abnormality, and the head CT examination showed no abnormality, but the patient had a lot of symptoms and was very worried, so he was admitted to the hospital for treatment. After the patient was admitted to the hospital, he was examined by a specialist: he was clear, he spoke fluently, his blood pressure was 120/80 mmHg, and his heart rate was 96 beats/min; his neurological examination did not show any obvious abnormality, and he scored 17 points on the Anxiety Scale and 20 points on the Depression Scale, so he was considered to be in a state of anxiety and depression, accompanied by sleep and wakefulness disorders. Head MRI showed small ischemic foci in the brain, MRA did not show obvious abnormalities, and DWI did not show diffusion limitation. The patient was given eszopiclone tablets and zolpidem tartrate tablets to be taken orally alternately, Paracetamol capsules to be taken orally to improve sleep, and venlafaxine hydrochloride capsules to be taken orally to improve depression, and psychological counseling and comforting were given to the patient at the same time. (Magnetic resonance results) III. Treatment effect After 5 days of treatment in our hospital, the patient’s condition was relieved and she was discharged from the hospital. The symptoms of difficulty in falling asleep and early waking mentioned by the patient at the time of consultation were significantly reduced, and the recent improvement in sleep, night dreams and nightmares were greatly reduced. As a result of the improvement in sleep after treatment, his mental state has been good recently. In addition, the patient reported that after treatment, his memory has improved, and his efficiency in work and study has continued to increase, so the patient is very satisfied with the treatment results. Note: We are glad that the patient’s symptoms have been improved after treatment. The patient had no sleep disorder in the past, but recently had difficulty in falling asleep, woke up early, and could not fall asleep easily after waking up, considering that the patient’s work and life stress is related, we suggest that the patient should relax his mood, divert his attention, pay attention to the combination of work and rest in the work and life in normal times, and drink a cup of hot milk and soak his feet in hot water at night before going to bed, all of which help to calm down the mind. Patients also have precordial discomfort, sigh-like breathing, and then row cardiology electrocardiogram, cardiac ultrasound and so on are not abnormal, consider somatoform disorders, mild anxiety and depression, can be in the improvement of sleep medication based on psychological guidance, family members should be timely persuasion, comfort. At home, sleep-improving sedative drugs should not be taken in excess, and the time should not be too long, or there may be dependence, inhibition of breathing and other side effects. V. Personal perception The patient in this case considered anxiety-depression-related insomnia, daily upset, agitation, irritability, nervousness and fear of restlessness, often with headache, dizziness, weakness, anorexia, palpitations, chest tightness and shortness of breath. The first step is to establish good sleep hygiene habits, learn to control and correct various behavioral and cognitive factors affecting sleep; the second is to rebuild the sleep pattern, restore the normal sleep structure and get rid of insomnia. If there is a sleep perception disorder, do not worry, timely medical treatment, timely treatment, the problem can be solved.