Hemolytic anemia is anemia due to many causes, including acute hemolytic anemia and chronic hereditary hemolytic anemia. However, in acute hemolytic episodes, there can be abnormalities in the blood count and a progressive decrease in red blood cells and hemoglobin in a short period of time, which means that the anemia can worsen rapidly in a short period of time. A significant increase in reticulocytes can be seen, and in the case of severe hemolysis, it can be accompanied by an increase in leukocytes. Therefore, routine blood tests are essential if hemolytic anemia is clinically suspected. In addition to routine blood tests, reticulocyte count must be done, or peripheral blood smear must be done to see the morphology of red blood cells. Therefore, in general, the routine blood count of hemolytic anemia will change in acute hemolysis, but the routine blood count alone cannot make the final diagnosis.