Hirudin is a component extracted from leeches, which has the effects of anticoagulation and reducing proteinuria, etc. Hirudin is more therapeutic than harmful to human kidneys; medicinal dosage can be used in the treatment of nephrotic syndrome, chronic nephritis and other disorders, but large dosage application will produce kidney damage. Hirudin has the effects of anticoagulation, antiplatelet aggregation, repair of kidney damage, and reduction of proteinuria; it can be used clinically in the treatment of nephrotic syndrome, chronic nephritis, and other diseases, which is beneficial to the recovery of kidney disease, but the application of hirudin in large doses can lead to kidney damage and the development of hematuria and other symptoms. Adverse effects of hirudin include nausea and gastrointestinal bleeding, and the drug is contraindicated in pregnancy and childbirth. Hirudin has both advantages and disadvantages for human kidneys, you need to use the medicine correctly under the guidance of your doctor, do not use the medicine on your own to avoid the related adverse reactions.