In ordinary life there are many accidents in which injuries can be sustained, and after surgery, when a defect is formed in the skull, many patients are very afraid, both of the dangers of not repairing the defect, and of the risks associated with repair surgery. In fact, cranial repair is just a routine surgery in neurosurgery, the purpose is to achieve coverage of the defect, there is almost no risk of failure. The most important thing for the patient to achieve the purpose of the surgery is the choice of the repair material. It is believed that many hospitals prefer titanium mesh, as the most widely used cranial repair material, although the price is easy to make the public accept, but it is not the best repair material, some patients have different degrees of rejection after using titanium mesh, and even the phenomenon of titanium mesh leakage. What is the best material for cranial bone repair? The emergence of a new material polyether ether ketone material, commonly known as peek material, has brought good news to many patients with cranial defects. The heat insulation of peek material is strong, the patient’s repair place will not have any feeling because of the change of the weather environment; it has excellent mechanical properties, strong resistance to impact, and can effectively protect the human brain tissue; from the point of view of cosmetic appearance, peek material is designed according to the patient’s CT data of the brain, and the use of 3D printing technology to make a perfect match with the bone window of the cranium; as a kind of non-metallic material, it is stable, can be repeatedly autoclaved at high temperatures and pressurized, and there is no risk of surgical infection, thus reducing the occurrence of complications. Therefore, cranial repair with peek material is an optimal choice for many people.