Barrett’s esophagus has been around for more than ten years. If there are no symptoms, no treatment is needed; if there are symptoms, treatment should be given as soon as possible. 1. No treatment is needed: If the patient has no obvious symptoms of Barrett’s esophagus, no treatment is needed and regular checkups are sufficient. 2. Medication: Barrett’s esophagus is mainly a complication caused by gastroesophageal reflux disease (GERD). Patients with acid reflux and heartburn can use proton pump inhibitors such as omeprazole enteric-coated tablets and gastric stimulants such as domperidone to alleviate their symptoms. 3. Surgery: If the patient has esophageal stenosis, esophageal epithelial cell heterogeneous hyperplasia and other manifestations, it is necessary to consider surgical treatment. Patients are advised to take reasonable treatment measures under the guidance of doctors, and should not take medication by themselves to avoid the development of the disease.