Pancreatitis part of the gland irregular hyperplasia mainly take drug treatment, including acid-suppressing drugs, gastric motivation drugs, mucosal protective agents, some patients need to take quadruple therapy. 1. Acid-suppressing drugs: such as omeprazole and rabeprazole, which can inhibit the secretion of gastric acid and avoid further damage to the cardia mucosa. 2. Gastric stimulant drugs: such as Mosapride, Domperidone, etc., help to improve gastrointestinal power, which is conducive to the digestion and absorption of food. 3. Mucosal protective agents: e.g. bismuth potassium citrate, aluminum thiosulphate, etc., which can help repair the damaged cardia mucosa. 4. Quadruple therapy: patients with H. pylori infection need bactericidal treatment, which is commonly used in the combination of four drugs. That is, a proton pump inhibitor such as omeprazole, rabeprazole, etc., a bismuth agent such as bismuth potassium citrate and two antibiotics such as amoxicillin, clarithromycin, furazolidone and other drugs. Combined with irregular glandular hyperplasia need to improve magnified gastroscopy according to the degree of atypical hyperplasia, and also need to be reviewed regularly. In addition, the above drugs may produce adverse reactions, if the adverse reaction is obvious need to stop or change drugs.