There are many reasons for the swelling and pain at the root of thigh, such as trauma, inguinal lymphadenitis, varicose veins with infection, etc. Its treatment mainly includes general treatment, drug treatment, physical therapy, surgical treatment and so on. 1. Trauma; when trauma injury to the inner thigh muscles, ligaments, etc., local edema can occur, and when the pain is severe, it should be braked in time, if it is a mild injury, pay attention to rest or cooperate with physical therapy such as massage, acupuncture, etc.; if it is accompanied by tendon or ligament tear, fracture, etc., it needs to be surgically treated to repair tendon, ligament, and reset the fracture end, fixation and so on. 2. Inguinal lymphadenitis: it can be manifested as swelling, fever, redness and other symptoms in the inguinal area, and its causative organisms are mostly Staphylococcus aureus, Escherichia coli, Streptococcus and so on, which need to be selected according to drug sensitivity test to choose the appropriate antibiotics, such as penicillin and so on. When abscess is formed in the lymph node, it should be punctured and drained in time. When the pain is obvious, it can be combined with non-steroidal anti-inflammatory drugs such as ibuprofen and celecoxib. 3. Varicose veins with infection: oral amoxicillin, levofloxacin and other drugs to fight infection, to be completely subsided after the inflammation, then you can undergo surgical treatment, surgical stripping of varicose veins, in order to avoid recurrent episodes of localized swelling and pain. There are many other causes of thigh pain, such as femoral head necrosis, hip fracture, etc. When thigh pain persists, you should consult a doctor in time to clarify the cause of the disease and then carry out targeted treatment. The above medications should be used under the guidance of a doctor.