Excessive renal excretion of potassium is commonly associated with long-term use of diuretics or excessive dosage. Long-term use of thiazide diuretics may lead to water and electrolyte disturbances, producing hyponatremia, hypochlorhydria and hypokalemia. So, how should excessive potassium excretion be diagnosed? The following is the diagnosis of excessive potassium excretion: 1. Skeletal muscle manifestations: when the general serum potassium <3.0mmol/L, the patient feels fatigue, weakness and fatigue; when <2.5mmol/L, general muscle weakness, limb weakness and weakened or disappeared tendon reflex. 2. Digestive system manifestations: nausea, vomiting, anorexia, abdominal distension, constipation, weakening or disappearance of intestinal peristalsis, intestinal paralysis, etc. 3. Central nervous system manifestations: atrophy, unresponsiveness, disorientation, drowsiness, coma. 4, circulatory system performance: early onset of myocardial stress, tachycardia, may have atrial, ventricular pre-term contraction; severe cases are hypokalemic cardiomyopathy, myocardial necrosis, fibrosis. 5, urinary system performance: long-term or severe potassium loss can lead to renal tubular cell degeneration, necrosis. Poor urine concentration function, thirst and excessive drinking, nocturia. In turn, potassium loss nephropathy occurs, and proteinuria and tubular urine appear. 6, metabolic system disorders: potassium deficiency, intracellular potassium deficiency, extracellular sodium ions and hydrogen ions into the cell, the distal tubular potassium ion and sodium ion exchange decreased, while sodium ion and hydrogen ion exchange increased, so lead to metabolic alkalosis and intracellular acidosis, and paradoxical acid urine. In patients with excessive potassium excretion, especially in fasting patients, they should be supplied with sugar and liquid by infusion, and if they have urine, they should be recharged with potassium in time. 0.2 g/(kg?d) for children; not too early, see urine to supplement potassium, not too early when renal insufficiency is not corrected.