Irbesartan tablets long-term use for the nervous system, vascular system and so on is a certain damage. 1. It will have an effect on the nervous system, manifested as dizziness, postural dizziness and so on. 2. Impact on the vascular system, resulting in patients with upright hypotension, but also some individual patients will affect the skeletal muscle, connective tissue, patients manifested as skeletal muscle pain. Irbesartan is to inhibit vasoconstriction and aldosterone release, producing a hypotensive effect. Irbesartan is a relatively safe drug for lowering blood pressure, and has a stable effect on lowering blood pressure. If patients with high blood pressure experience adverse reactions while taking Irbesartan, please go to the hospital in a timely manner, under the guidance of the doctor’s reasonable use of medication, do not blindly discontinue and change medication.