Tubular atrophic lesion, or focal segmental glomerulosclerosis (FSGS), is a common primary glomerular disease in children and adults with nephrotic syndrome (NS). It is characterized histopathologically by segmental glomerular scarring with or without intra-glomerular capillary foam cell formation and adhesions. Focal means that only part of the glomerulus is involved (50% of the glomerulus is involved); segmental means that part of the glomerular lobules are involved; and glomerulosclerosis means staged glassy changes or scarring of the entire glomerulus. Pathological features are mostly associated with tubular atrophic lesions and interstitial fibrosis. Small tubular atrophy lesion patients diet considerations: 1, small tubular atrophy lesion patients eat less salt, alkali, our normal adult daily salt intake of about 5-6 grams, some areas eat salt per person per day to 12 grams, salt for sodium chloride, alkali for sodium carbonate, soda for sodium bicarbonate, eating too much salt and alkali containing sodium, easy to make water retention in the body, inducing edema, so for renal Edema patients should control the amount of salt and alkali intake, 2-3 grams of salt per person is a low-salt diet. Salt-free diet is also unscientific, easy to weakness, dizziness, etc. over time. 2, normal people urine volume generally 1-2 kg a day, acute nephritis, acute renal failure oliguric period and nephrotic syndrome, chronic renal failure with oliguric swelling patients, to control the amount of water intake. Because drink in not out, water retention in the body to aggravate edema, but also easy to aggravate hypertension, the amount of water into the urine plus 500 ml is appropriate. The amount of water intake can be relaxed after the increase of urine volume. The amount of water intake for patients with normal urine volume is not limited. In addition, patients with urinary tract infections such as acute pyelonephritis, urethritis, cystitis, etc., in addition to timely consultation and medication, more water, more urination is very beneficial to the recovery of the disease. 3, fish, shrimp, eggs, meat food, fish and shrimp food for high-quality protein, in allergic diseases such as allergic purpura, purpura nephritis due to suspicion of heterosexual protein allergy or a history of fish and shrimp allergy must be used with caution, is generally not contraindicated. Fish, shrimp, eggs, meat food rich in animal protein, is the body’s cells, tissues, the main building material, very important to the human body, after eating protein-containing food liver decomposition, kidney excretion, so when the kidney function is reduced, to reduce the amount of protein intake to meet the body’s metabolic nutritional needs, but also does not increase the burden on the kidneys as the principle. Some patients are afraid to eat protein because their kidney disease is not serious, or they do not care when their condition requires protein restriction is not correct.