Anti-edema furosemide tablets and spironolactone tablets can be taken together to help maintain electrolyte balance while eliminating edema and improving symptoms. Furosemide Tablets is a tabular diuretic, used to treat edematous disorders caused by heart failure, kidney disease, cirrhosis of the liver and other diseases, producing diuretic effect and eliminating edema, but Furosemide Tablets is a potassium-excreting diuretic, discharging water at the same time, the potassium ions will be discharged along with the urine, and it may produce hypokalemia, hyponatremia, and other electrolyte disorders such as the adverse reactions. It is strictly prohibited for people with severe hepatic and renal impairment, low potassium and low sodium. Spironolactone is an aldosterone competitive inhibitor, with the effect of potassium-preserving diuretic, which can effectively reduce the excretion of potassium ions and maintain the balance of potassium ions, thus contributing to the correction of electrolyte disorders, which may produce hyperkalemia, gastrointestinal discomfort and other adverse reactions, and is strictly prohibited for the use of this drug in hyperkalemic people. There is no contraindication to the combined use of anti-edema furosemide tablets and spironolactone tablets. In clinical practice, the two drugs are often used together to reduce electrolyte disorders while producing diuretic effects. The medication should be used appropriately under the supervision of a physician.