Chest pain and tightness may be due to coronary heart disease, costochondritis and other diseases, need to first clear diagnosis, and then can be relieved by medication, surgical treatment and other ways. 1. Coronary heart disease: atherosclerosis of the coronary arteries caused by the narrowing of the lumen leading to insufficient blood supply to the heart caused by the disease, often manifested clinically as exertion or emotional excitement after chest pain, chest tightness, shortness of breath and other symptoms. Nitroglycerin can be taken under the tongue to relieve the blockage of serious need for percutaneous coronary intervention. 2. Costal chondritis: it refers to the inflammation of the cartilage at the junction of the ribs of the sternum, which can be manifested as chest tightness, chest pain and other symptoms, chest pain in a fixed location, often because of the pain aggravated by inhalation and dare not breathe. Can be treated by applying antibiotics such as penicillin, etc., and ibuprofen and other drugs can be used to relieve pain when the pain is severe. The symptoms of chest pain and feeling breathless, you need to go to the hospital in time, improve the relevant examination such as arteriography, etc., to clarify the cause of the disease, under the guidance of the doctor symptomatic treatment, avoid unauthorized use of drugs.