Progesterone 18ng/mL at 6 weeks of pregnancy is mostly a normal presentation.
Progesterone has a role in maintaining the decidualized endometrium, relaxing the smooth muscle of the uterus, improving the uterine blood supply, and immunomodulation in early pregnancy.
The level of progesterone in the body fluctuates, and its production and secretion is regulated by luteinizing hormone (LH) secreted by the pituitary gland, which is secreted in a pulsatile, cyclic manner, and therefore the production of progesterone is also pulsatile and cyclic.
Currently, expert consensus does not recommend checking progesterone during pregnancy because the pulsatile secretion level of progesterone fluctuates greatly in early pregnancy, sometimes as low as 5 ng/ml. progesterone is basically at a plateau in the range of 6-10 weeks’ gestation, with a physiological drop and then a rebound in the range of 7-9 weeks’ gestation.
Women at different times, progesterone values vary, can not be generalized, in general 6 weeks pregnant progesterone 18ng / mL, most of the normal performance.
Early pregnancy should be closely observed whether there is abdominal pain, vaginal bleeding and other uncomfortable symptoms, and according to their own situation to give appropriate measures to deal with.