Gastroesophageal reflux (GER) is the reflux of gastric contents into the esophagus and even the oropharynx, with vomiting as the main clinical manifestation, which can cause a series of intra- and extra-esophageal symptoms and/or complications that need to be evaluated and treated. The clinical manifestations of gastroesophageal reflux in children are diverse and can be broadly classified into three categories: typical symptoms, atypical symptoms and extra-digestive symptoms. Typical symptoms: vomiting is the main symptom, infants and young children: milk spillage, regurgitation; older children: acid reflux, regurgitation, belching, burning sensation behind the sternum or under the saber, and in severe cases, vomiting blood and black stool. 2. Atypical symptoms: refusal of food/difficulty in swallowing, epigastric pain, chest pain, weight loss or no gain, poor growth, anemia, irritability, night terrors. 3. Extra-digestive symptoms: refractory bronchial asthma, recurrent pneumonia, apnea or sudden infant death syndrome, wheezing, hoarseness, chronic cough; chronic pharyngitis, otitis media, sinusitis, oral ulcers, etc. Children who present with atypical symptoms or symptoms outside the digestive tract should be taken seriously by the clinician.