HPV high-risk positive is not recommended to have intercourse because HPV high-risk infection suggests that there will be high-risk HPV virus in the cervix and vagina, and if there is contact at the same time of treatment it is able to cause new HPV virus infection opportunity, and the effect of virus treatment will be affected. New viral invasion can lead to a new replication cycle, resulting in the multiplication of a large number of viral particles, which can affect the effectiveness of treatment. In the clinical treatment of viral infection is best to prohibit sexual intercourse, and if unavoidable should also try to use isolation measures, such as the use of condoms, can play a role in a certain degree of deterrence, so as to make the effect of treatment more obvious, so as to minimize the chance of reinvasion of the virus.