1, age: generally refers to people over 40 years old, now the age of onset of diabetes is getting lower and lower, with the growth of age, the human metabolic rate decreases, resulting in obesity, fat causes insulin resistance. There is no way to control the age factor. Wu Jian, Department of Internal Medicine, Shanghai Integrated Hospital of Traditional Chinese and Western Medicine 2, people with a family history of diabetes: the genetic factor of diabetes accounts for 50% of the onset factors. People with a family history of diabetes, even if they take good preventive measures, still have a high chance of getting diabetes. Of course, it does not mean that people without a family history are safe, these people do not pay attention to the influence of environmental factors, do not pay attention to take measures to prevent diabetes. Once they get diabetes, their family has a history of diabetes. In general, the children of type 2 diabetics are more likely to get diabetes, especially if both parents are diabetics. children of type 1 diabetics do not all get diabetes, but there is still a potential risk of heredity. 3, overweight or obese: obesity causes insulin resistance, insulin resistance is likely to induce diabetes. Obesity is a very important factor, but also controllable factors. Human controllable causes of death, the first is smoking, the second is obesity. Obesity makes the fat cells become particularly large, while the insulin receptors on the fat cells become less and less, insulin action is poorer, resulting in insulin resistance, insulin resistance tends to cause excessive secretion of insulin, excessive secretion of insulin can not last a long time, the pancreatic islet cells will eventually be overwhelmed and functional failure, which triggers diabetes. Obesity is also a preventable factor. People with a family history of type 2 diabetes can delay the onset of diabetes and make it less severe if they avoid obesity. 4. People who have ever had high blood glucose such as fasting blood glucose ≥ 5.6mmol/L, or oral glucose tolerance test for 2 hours ≥ 7.8mmol/L but <11.1mmol/L, are also at risk of diabetes. People with this condition should check their blood glucose regularly and take prompt action if they are found to be abnormal. 5. Women who have given birth to a huge baby of more than 8 pounds or have gestational diabetes have a higher risk of getting diabetes. This is mainly because the pregnant woman's blood sugar used to be high when she was pregnant, and she didn't pay attention to it at the time and didn't find out that she had diabetes. When the blood sugar is higher, the child gets more sugar, and the excess sugar makes the child grow larger and become a giant baby. Women who have had huge babies now have normal blood sugar and still need to be extra careful. The traditional Chinese custom is to think that having a fat child is a good thing, but from a medical point of view, having a fat child is not necessarily a good thing. 6, people with hypertension, dyslipidemia, hyperuricemia, fatty liver, hyperinsulinemia, atherosclerotic cardiovascular disease are prone to diabetes, and these people should be the focus of diabetes prevention. 7, long-term treatment with antipsychotic or antidepressant drugs, life and work stress, the existence of poor diet and lifestyle habits, lack of physical activity is also a high-risk group of people with diabetes.