Doxycycline hyclate is an antibiotic that belongs to the tetracycline group of antibiotics. Hygromycin is a tetracycline antibiotic, belonging to the bacteriostatic group, and is able to be used for the multi-treatment of infections with a wide range of pathogens. It can specifically bind to the A position of the 30S subunit of the bacterial ribosome, inhibiting the growth of bacterial peptide chains as well as the synthesis of proteins, thus exerting a bacteriostatic effect. Satomycin can be used to treat rickettsiae, chlamydia, spirochetes, mycoplasma, etc. However, due to the misuse of antibiotics, positive bacteria such as staphylococci and numerous gram-negative bacilli are resistant to hygromycin. The use of oxytetracycline is prohibited in pregnant women, lactating women, children and people who are allergic to tetracyclines. Doxycycline hyclate has some adverse effects, such as nausea, vomiting, bloating, diarrhea, etc. A small percentage of people who take it also experience allergic reactions, such as hives. The use of oxytetracycline should be carried out under the guidance of a professional physician, and when an adverse reaction occurs, consult a physician in a timely manner, treat accordingly, and adjust the medication.