Neck and shoulder stiffness in patients with hypoglycemia is generally not related to hypoglycemia, but may be caused by bad life habits or cervical spondylosis, frozen shoulder, etc. Conservative treatment, medication or surgical treatment can be carried out according to the cause of the disease, meanwhile, oral supplementation of glucose or intravenous supplementation of glucose can be carried out for the treatment of hypoglycemia. 1. Bad life habits: if the patient sits or stands for a long time, and often looks down at the cell phone, it may cause neck and shoulder stiffness. Timely improvement of sitting posture and correction of bad living habits are needed for treatment. 2. Cervical spondylosis: It is a kind of cervical spine degenerative disease, which can cause stiff neck and shoulder when the condition is serious. Most patients can utilize traction therapy to alleviate the symptoms; if the condition is serious, surgery is required. 3. Frozen shoulder: It is a sterile inflammatory disease, and the treatment of this disease requires attention to rest and reduce the burden on the shoulder and back muscles. If the symptoms are serious and cause pain, medication can be taken as prescribed by the doctor to relieve pain. If the condition is serious, open surgery or arthroscopic minimally invasive surgery is feasible. 4. Hypoglycemia: once the symptoms of hypoglycemia appear, sugar water or sugary food should be given in time. If the symptoms do not get better or aggravate significantly, it is recommended to consult a doctor in time, to clarify the cause of the disease, and standardize the treatment in accordance with the doctor’s instructions. Hypoglycemia patients with neck and shoulder stiffness should be treated under the guidance of professional physicians.