Mucus with blood in the stool is considered to be possibly related to perianal disease, rectal disease, colon disease and other factors. The main drug treatment and surgical treatment. 1. Perianal diseases: such as hemorrhoids, anal fistula, perianal abscess, etc., there will be mucus and blood on the stool, usually blood will not be mixed with the stool, just stay on the surface; generally surgical treatment. 2. Rectal diseases: such as bacterial dysentery, rectal tuberculosis, rectal polyps, rectal cancer, etc., in addition to mucus and blood in the stool, often accompanied by diarrhea, anal pain and other symptoms; if dysentery and tuberculosis generally need antibiotics and other medications, such as norfloxacin, etc.; if polyps and tumors generally need surgical resection treatment. 3. Colon diseases: such as Crohn’s disease, ulcerative colitis, colon cancer, colon polyps, etc., some patients will also appear in the stool with mucus and blood, for Crohn’s disease commonly used aminosalicylic acid preparations for treatment, such as: salicylazosulfapyridine. Such as for ulcerative colitis patients commonly used mesalazine and other drugs, if polyps and tumors, also to surgical treatment. All of the above drugs should be applied under the guidance of a doctor, if there are symptoms of mucus and blood in the stool, it is recommended to go to the hospital as soon as possible, under the guidance of the doctor’s treatment.