In clinical craniotomy, the probability of being awakened is close to zero, because craniotomy is a very high-risk surgery, requiring the patient to lie motionless on the operating table. For the anesthesia requirements are very high, must be accompanied by the whole process, so as long as the discovery of a little abnormal situation, need to immediately give drugs to deepen the anesthesia, only in this way can ensure the safety of the operation. Therefore, it is very difficult to wake up the patient in an ordinary surgery, such as common brain hemorrhage, brain tumor, cerebral infarction and other surgical procedures, it is impossible to be woken up. Except in some special diseases, such as Parkinson’s or epilepsy, these functional diseases, need to be carried out in the local anesthesia aspect of the implementation of deep electrode implantation surgery. It is possible to be awakened during this procedure, but the patient will be informed of the precautions to be taken prior to the surgery, so it is not possible to be awakened during routine surgery.