Duloxetine Hydrochloride Tablets generally have more side effects than Sertraline Hydrochloride Tablets. Duloxetine Hydrochloride Tablets can be used to treat depression and anxiety, which can control the depressed mood of patients and can improve the action of the central nervous system. Duloxetine Hydrochloride Tablets have more side effects and after taking the medication, patients may experience adverse reactions such as dizziness, nausea, diarrhea, slight increase in blood pressure, insomnia and other symptoms. It is contraindicated for people who are allergic to the drug, pregnant women, etc. It is used with caution for people with heart disease, high blood pressure, stomach problems, etc. Sertraline hydrochloride tablets is a kind of antidepressant drug, belongs to the 5 hydroxytryptamine reuptake inhibitor, can be used for the treatment of anxiety disorders, depression, obsessive-compulsive disorder, hypochondriacal disorder and other psychological disorders. Sertraline Hydrochloride Tablets do not have many clinical side effects, commonly include nausea, vomiting, abdominal pain, constipation and other symptoms. It is forbidden to use for people with allergy and severe liver dysfunction, while it is not suitable for patients with renal dysfunction, pregnant women and lactating women. When taking the two drugs, they should be taken under the guidance of a doctor and should not be taken without authorization to avoid adverse reactions.