1. For mothers with hepatitis B, the newborn baby should be immunized with hepatitis B vaccine and hepatitis B immunoglobulin within 24 hours immediately after birth. It is recommended that the sooner the better. According to this current method, breastfeeding is possible after immunization. 2. The current mother-to-child blockade failure is often due to intrauterine infection occurring late in pregnancy. There is evidence of high maternal serum load and increased immunization failure rate in newborns. If you want to further reduce the probability of transmission, you can add oral antiviral therapy after 24 to 28 weeks of gestation, which can be used in the form of telbivudine, lamivudine, tenofovir. 3. In patients who become pregnant during oral antiviral therapy such as entecavir, it is recommended that the pregnancy can be continued by switching to telbivudine, lamivudine or tenofovir, and termination of pregnancy is not recommended. 4. There is no correlation between normal delivery and caesarean section and the chance of mother-to-child transmission.