Yellowing on both sides of the nose may be a manifestation of endocrine disorders, and may also be caused by hemolytic anemia, low liver cell function, etc. 1. Endocrine disorders: endocrine disorders due to prolonged late night, tension, stress, etc., resulting in facial skin lusterless, yellowish, so the yellowing of the skin on both sides of the nose, you need to avoid staying up all night, relaxation and so on to alleviate. 2. Hemolytic anemia: when hemolytic anemia occurs, the red blood cells dissolve and destroy too much, producing too much bilirubin, too much bilirubin will be deposited on the skin and sclera, thus showing yellowing on both sides of the nose. 3. Low function of liver cells: due to low function of liver enzymes, or due to advanced cirrhosis, or fulminant hepatitis, liver failure, can not take up the unconjugated bilirubin in the blood, resulting in a higher concentration of unconjugated bilirubin in the blood and jaundice, which can be manifested as yellowing of the skin on both sides of the nose. Physiologic jaundice in newborns is also due to this reason. When yellowing on both sides of the nose, you should first go to the hospital to find out the cause and then treat it, and do not use your own medication.