Marburg virus and Ebola virus belong to the filovirus family of hemorrhagic fever viruses. Up to now, outbreaks of Marburg virus have been concentrated in southern and eastern Africa, with rare outbreaks in Asia and even China. The virus has a high mortality rate, high transmission rate, easy to cause outbreaks of epidemics and other characteristics, the onset of severe hemorrhagic fever in a short period of time, and accompanied by multi-organ and immune system damage symptoms. 1, the source of infection: patients and animals carrying Marburg virus; 2, the transmission route: mainly through direct contact with the infected person’s blood, secretions, organs or other body fluids, as well as the surface of objects contaminated by the infected person’s body fluids, etc. (such as clothing, towels). (e.g. clothes, towels). However, burial customs in some African regions are also one of the reasons for the spread of the disease; 3, susceptible groups: people in close contact with the corpse of an infected person, children, or people in poor health, suffering from serious chronic diseases, such as diabetes, heart disease, pulmonary heart disease, etc.; 4, symptoms of infection: after the incubation period of Marburg virus, patients can suddenly develop headaches, fever, muscle aches, diarrhea, vomiting and other flu-like symptoms. However, the virus can then attack multiple organs at the same time in a short period of time, resulting in severe bleeding from the gums, nasal cavity, mouth, vagina and other body orifices, and eventually death due to extensive internal bleeding, hemorrhagic shock, brain damage, etc.; 5. Treatment: There are no specific drugs or vaccines approved for the treatment of Marburg virus, so the key part of treatment focuses on close monitoring of vital signs, fluid resuscitation, electrolytes and acid-base monitoring, and management of co-infections and organ dysfunction to improve the patient’s chances of survival; 6. Prevention: For the normal population, contact with diseased animals should be avoided in areas where infected individuals are present. Early in the course of the disease, because clinical symptoms of Marburg virus are difficult to distinguish from other tropical febrile diseases such as malaria, typhoid fever, and rickettsial infection, prompt reporting or medical consultation should be made after the appearance of similar symptoms of infection.