Chronic atrophic gastritis C3 with erosions can be treated with lifestyle modification, medications, and should be treated surgically if there is a possibility of localized lesions. Endoscopically atrophic gastritis is categorized as open as well as closed, O as open and C as closed. Depending on the extent, closed atrophic gastritis is further divided into C1, C2 and C3. chronic atrophic gastritis C3 with erosion means that the atrophy is close to the cardia, and erosion occurs at the same time. 1. Lifestyle regulation: pay attention to diet in daily life, avoid spicy food stimulation, avoid overeating, and increase physical exercise, regular gastroscopy to observe the recovery situation and prevent the occurrence of cancer. 2. Drug therapy: clinically, gastric acid inhibiting drugs such as omeprazole and gastric mucosa protecting drugs such as bismuth potassium citrate can be used to treat chronic atrophic gastritis C3 with erosion. At the same time, the presence of Helicobacter pylori infection should also be clarified, and if there is Helicobacter pylori infection, the quadruple method, i.e., a proton pump inhibitor such as omeprazole + a bismuth agent such as bismuth pectin + two antibiotics such as amoxicillin and clarithromycin, should be used for eradication treatment. 3. Surgery: If there is a localized lesion, the lesion can be completely removed by surgery to prevent the disease from worsening. Chronic atrophic gastritis C3 with erosion should go to the hospital in time, please follow the doctor’s instructions for medication.