Both pepsinogen l and 2 are high and need to be treated.
Pepsinogen is synthesized by the main cells of the acid-producing glands, and is transformed into pepsin by hydrochloric acid and active pepsin in the stomach. Elevated pepsinogen L is related to excessive secretion of gastric acid.
Elevated pepsinogen 2 is considered to be related to atrophy of the gastric fundus glandular tube, gastric epithelial hyperplasia or pseudo-pyloric glandular hyperplasia with heterogeneous value added, etc. If both pepsinogen L and LL are on the high side, it is considered that there are some gastric disorders, such as Helicobacter pylori infection, chronic superficial gastritis, etc., which need to be actively treated.
The course of pepsinogen to gastric diseases can be described as superficial gastritis, gastric mucosal erosion ulcer, atrophic gastritis, gastric cancer, etc., so if there is no timely intervention, it may develop into gastric cancer.
If both pepsinogen l and 2 are high, it is recommended to consult a doctor in time to clarify the cause of the disease with the help of the doctor and to carry out targeted treatment or therapy.