Hydrochlorothiazide is usually not recommended for those with hyperglycemia, hypokalemia, and hyperuricemia. Hydrochlorothiazide belongs to thiazide diuretics, which can reduce extracellular volume and lower peripheral vascular resistance after use. It is mainly used in the treatment of hypertension, nephrogenic uremia, nephrotic syndrome, early stage of chronic renal failure, water retention and other diseases. Usually, the use of this drug may reduce glucose tolerance and increase blood sugar, so it is not recommended for people with hyperglycemia. It also interferes with the excretion of uric acid from the renal tubules, which may induce gouty attacks and is not recommended for hyperuricemia, and it can cause a decrease in potassium in the blood, so it is not recommended for hypokalemia. Secondly, it is contraindicated for those who are allergic to the ingredients of the drug. During the use of the drug, it is necessary to monitor electrolytes, blood pressure, liver and kidney function. At the same time, the drug should be taken from the smallest effective dose, thus reducing the incidence of side effects and aldosterone secretion. Pregnant and lactating women should use the drug under the supervision of a doctor. If you need to choose hydrochlorothiazide treatment due to your condition, it is recommended that you consult a doctor in time to decide on the dosage and learn the precautions after a comprehensive assessment of your condition.