Antibody negativity means that the antibody component of the test is not present in the body, suggesting that there is no resistance to the specific disease, but also indicating that the corresponding pathogen may not be present in the short term. Antibodies are immunoglobulins formed by lymphocytes after the immune system comes into contact with foreign pathogens or antigens, which can play a role in destroying foreign pathogens, thus effectively resisting foreign infections. Therefore, the antibody test can initially analyze the infection situation and immune ability. Negative antibody tests indicate that specific antibodies are not present in the subject’s body, suggesting that the immune system has not been stimulated to produce antibodies as a result of a previous infection with the pathogen in question. This result suggests that the person is not immune to the specific pathogen and may be considered for vaccination. Antibody testing can be used both before and during an infection, but it is important to identify whether symptoms of infection were present at the time of sample collection and the specific antibody residuals that will help analyze the results.