Bile reflux is a dysfunction of the pyloric sphincter usually due to a disturbance of the pyloric function of the stomach. Bile reflux is usually caused by the damage of weakly alkaline bile to the gastric mucosa, and the therapeutic effect of sodium bicarbonate is unsatisfactory, and it is necessary to apply mucosal protective agents that neutralize the effect of bile, such as magnesium aluminum carbonate. At the same time, the stomach of people with bile reflux secretes more gastric acid, due to excessive gastric acid easily cause acidity, heartburn sensation, stomach pain and other discomforts, sodium bicarbonate tablets have the effect of neutralizing gastric acid, which can be used as an adjunctive treatment to help people with bile reflux to alleviate the problem of excessive gastric acid. The process of taking sodium bicarbonate tablets to neutralize stomach acid may cause belching, stomach pain, stomach distension, secondary to increased acid secretion, and other adverse reactions; sodium bicarbonate contains relatively high sodium, which may cause edema or elevated blood pressure due to sodium accumulation after eating, and in addition, muscle spasm, muscle weakness, alkalosis and other adverse reactions may also occur after the use of the drug. Allergic to sodium bicarbonate tablets ingredients, patients with restricted sodium intake, and those who are using urotropin are prohibited from using the drug, and those with bile reflux should be guided by a doctor to take sodium bicarbonate tablets, and should not use the drug arbitrarily.