Excessive sweating of the palms should be considered as hand sweating disorder. The specific cause of its pathogenesis is unknown and may be related to environmental factors, endocrine disorders, hormone level disorders and neuropsychiatric factors. In terms of treatment, you can choose topical antiperspirant treatment, such as 20% aluminum chloride alcohol solution, 5% alum solution, 3%-5% formaldehyde solution, etc. If the sweating is caused by neuropsychiatric factors, such as anxiety and tension, you can choose to use anti-anxiety drugs such as doxepin, diazepam, etc. You can also choose sedative drugs, such as phenobarbital and isopentobarbital. If the drug improvement is not good, you can choose local botulinum toxin A injection, by inhibiting the excitability of nerve conduction, so as to achieve the purpose of inhibiting local sweating. To completely treat hand sweating, it is recommended that you can choose surgical treatment.