Diffuse hepatic injury refers to diffuse injury of the liver parenchyma, which is mainly caused by liver fibrosis. Diffuse hepatic parenchymal injury is an expression of the pathology at the time of imaging, which generally suggests that the morphology of the liver is now altered, with a number of specific pathogenic causes, which may be due to fatty liver, chronic alcohol consumption, or chronic viral infections. The patient has entered a state of chronic hepatitis in which the normal structure of the hepatic lobules is disrupted and fibrosis of the liver occurs. When diffuse lesions of the liver parenchyma occur, it is important to take timely treatment, which is usually reversible. If treatment cannot be taken in time, it will cause the degree of lesions to continue to accelerate, and liver fibrosis will eventually form cirrhosis, and once cirrhosis is formed, it is basically irreversible.