The skull is not only the protective layer of soft tissue in the brain, but it is also important for maintaining the aesthetics of the head. And life is often full of accidents, perhaps an inadvertent collision will make our skull lose a piece. If not repaired in time, not only the normal functional environment of the brain can not be guaranteed, but also will cause a great burden on the patient’s psychology. What materials are available for repairing the skull? For skull repair surgery, the material is the most important thing. A good material can not only improve the success rate of surgery. It also reduces the chance of post-operative complications. Thousands of years ago, some doctors tried to use various materials for skull repair, but limited to the backwardness of medical knowledge and technology at that time, there were no suitable materials for doctors to choose. With the advancement of medicine, more and more cranial repair materials have become available for use. Plexiglass, light apatite and calcium phosphate bone cement materials, which were once used in clinical practice, have been gradually withdrawn from the medical stage due to their poor clinical effects. Nowadays, the commonly used cranial bone repair material is titanium mesh, which is also a high-quality material that has been used for a long time with good results. However, the metal properties of titanium mesh often bring consequences such as sensitivity to hot and cold reactions and CT imaging errors to patients. Under the efforts of medical researchers, a new type of cranial bone repair material has been applied to the clinic, and we use polyether ether ketone PEEK material. This is a polymer biomaterial, in terms of elasticity, heat conduction, hardness, stability and other aspects of the human skull is very close to the use of three-dimensional molding after the PEEK bone plate, and the skull structure can be a perfect fit, do not have to worry about the accuracy and aesthetics of the problem. Numerous clinical cases have shown that there is no discomfort or complication caused by PEEK cranial bone repair materials, so PEEK is undoubtedly a wonderful choice for cranial bone repair.