The skull not only maintains the integrity of the appearance of the head and face, but also serves as an important barrier connecting the cranium with the outside world. Cranial defects are mainly common after various traumatic injuries and debridement and decompression surgeries, such as accidents, falling objects, cranio-cerebral surgery and so on. If the area of cranial defect reaches more than 3*3cm, it is unquestionable to do cranial repair surgery, only in this way can we avoid more injuries and complications in time. However, many patients don’t know much about cranial repair surgery, such as the materials used for the repair and the full cost of cranial repair surgery. Cranial Repair Surgery is a common surgical procedure, the cost of repair surgery is related to the examination fee, hospitalization fee, material fee and surgery fee, the purpose of the surgery is to take the repair material to repair the defective area in a good way. Titanium mesh is currently used as the most commonly used cranial bone repair material, its price is not high, but there are great defects, the postoperative effect is not good, so cranial bone repair also need to choose more advanced repair materials. With the progress of modern science and technology, polyetheretherketone peek material has become the ideal choice for cranial bone repair surgery, although the price of this material is a little more expensive, but the effect is very superior. We use polyether ether ether ketone peek cranial bone repair material as the basis of cranial bone repair implant material, at the same time introduced the concept of plastic surgery, in the basis of 3D printing, for different patients to develop a personalized peek cranial bone repair plastic surgery program, to achieve the appearance of repair plastic surgery and cosmetic surgery at the same time, to reduce postoperative complications. It is recommended that patients go to regular hospitals as soon as possible to take the appropriate repair materials to actively repair and restore health as soon as possible.