Gastric fundus mesenchymal tumor 4 cm is more serious. Gastric fundus mesenchymal stromal tumor is a tumor of mesenchymal tissue origin in the digestive tract, and will also appear in the small intestine, esophagus, colon, rectum, liver and other parts of the potential malignant tumors, can appear nausea, vomiting, abdominal pain, anemia, mass, fever, upper gastrointestinal bleeding and other clinical symptoms. The main treatment means of gastric fundus mesenchymal tumor is surgical resection, and the surgical method is mainly gastric wedge resection, which has a high recurrence rate, and drug-targeted therapy can be carried out according to the pathology after the operation; gastric fundus mesenchymal tumor is not sensitive to radiotherapy and chemotherapy, and it is recommended that patients improve the abdominal CT, abdominal magnetic resonance examination and other examinations to evaluate the condition regularly. Normally, the diet should be light and avoid spicy and stimulating food. This disease is highly specialized, should go to regular hospitals in time, determine the specific treatment plan under the guidance of the doctor, and actively cooperate with the treatment to avoid deterioration of the condition.