One night of no sleep does not usually cause sudden death, but frequent all-nighters will definitely increase the risk of inducing sudden death. Normal adults need 6~8 hours of sleep per day, while maintaining good sleep habits helps to form high quality sleep and relieve fatigue. 24 hours without sleep, in addition to the endocrine system, gastrointestinal system has a greater impact on the cardiovascular and cerebrovascular harm is greater; a long period of time without sleep will cause cerebral ischemia, oxygen deprivation, dizziness and nausea, but also cause myocardial ischemia, triggering arrhythmia, serious will cause cardiac arrest. For the sake of their own health, we must ensure adequate sleep, regular work and rest, avoid staying up late, not to mention overnight, if you have symptoms of physical discomfort, you should go to the hospital in a timely manner, consult a physician for guidance.