Anal and scrotal itching and cracks, generally considered to be related to scrotal eczema, anal fissure, warts and other factors, the specific situation needs to be diagnosed according to the clinical manifestations and test results, and carry out the appropriate treatment. 1, scrotal eczema: mainly due to bad habits, sweating, do not pay attention to cleanliness and hygiene caused by the scrotum and the surrounding skin itching, redness and swelling, due to the skin hard knots, the situation is serious will be The skin will become cracked, resulting in anal and scrotal itching and cracking. It can be treated with topical glucocorticoid cream and oral loratadine, azathioprine and other medications under the guidance of a doctor; 2, anal fissure: due to prolonged constipation, dry stools lead to mechanical damage to the anus and the surrounding tissues, which is mainly manifested as pain in the anus or bleeding phenomenon, resulting in itchy anus and scrotum and cracks. It can be treated by local application of analgesic drugs such as lidocaine gel, and patients with serious conditions can be treated with anal fissure resection, lateral internal sphincter amputation, etc.; 3, condyloma acuminatum: due to unclean sexual behavior leading to human papillomavirus infection, which involves the scrotum, the perianal skin, and stimulates the local skin, which results in the appearance of itching and cracking of the anus and scrotum, and red warts, which are often accompanied by a foreign body sensation, stinging, and a feeling of pain, and are often associated with a feeling of pain. Often accompanied by foreign body sensation, itching and other symptoms. You can use fluorouracil cream, onychotoxin and other treatment under the guidance of a doctor, or laser, liquid nitrogen freezing and other ways to treat, and local application of recombinant human interferon α2b gel, to prevent recurrence. Causes of anal and scrotal itching and cracking more causes, the specific circumstances need to be examined in the regular hospital, and then actively treated. Daily life should develop good hygiene habits, for the prevention of such conditions have a certain role.