The combination of atorvastatin and ezetimibe may enhance the cholesterol-lowering effect, while liver function should be monitored.
Atorvastatin and ezetimibe are both cholesterol-lowering drugs in clinical practice. Atorvastatin belongs to the class of statin, which inhibits the key enzyme of cholesterol synthesis; Ezetimibe belongs to the cholesterol absorption inhibitor, and both of them have different mechanisms of action, so the combination of them can enhance the effect of lipid-lowering. At the same time, because both have a certain effect on liver function, the liver function should be tested after the combination of drugs.
Atorvastatin is suitable for people with hypercholesterolemia and coronary heart disease. Atorvastatin is contraindicated in people who are allergic to the drug, as well as pregnant and lactating women, active liver disease or unexplained elevation of aminotransferases. Adverse reactions such as myalgia, rhabdomyolysis, elevated liver enzymes, and abdominal distension may occur after administration.
Ezetimibe is indicated for the treatment of hypercholesterolemia. Contraindications are the same as for atorvastatin. Adverse reactions include myalgia, dizziness, cholecystitis, and constipation.
Please consult a medical professional before using the drug.