The protective effect of any vaccine is not 100%, and vaccination with the new coronavirus vaccine can reduce the risk of infection to a certain extent, but there is still a risk of infection. The protective effect of the new coronavirus vaccine has now been verified to a certain extent in our fight against the epidemic, i.e. the rate of severe illness and mortality are not high. However, infection can still occur after vaccination with the new coronavirus vaccine because the protective effect produced by the vaccine varies in different people, and some people may not produce protective antibodies after vaccination. Infection may also occur if the vaccination period is still short or if the antibody titer drops after vaccination. Vaccines are also challenged by the variability of the virus, which can also result in a decrease in the effectiveness of the vaccine against the mutated virus. Vaccination against novel coronaviruses can still be an effective means of outbreak control. Even after vaccination, it is still important to take personal precautions on a daily basis. Maintain a safe social distance, wear masks properly when going out, wash hands frequently, ventilate the room and avoid gathering. Exercise properly to enhance personal fitness.