Contraindications to vertebroplasty can be divided into absolute contraindications and relative contraindications. Absolute contraindications are as follows: 1, asymptomatic stability fractures are generally treated conservatively and do not require excessive intervention; 2, patients with fractures, after certain treatment with drugs, there is significant pain relief and improvement in all aspects, it is recommended that vertebroplasty should not be considered as far as possible; 3, patients without evidence of acute fractures for prophylactic treatment, fractures through conservative treatment for a period of time, there is significant relief of symptoms. Further conservative treatment can be performed to obtain a relatively stable clinical outcome, without the need for prophylactic line vertebroplasty surgery; 4, the patient may have underlying disease, or the risk of surgery will be further increased, such as uncorrected coagulation dysfunction, bleeding body. If the patient has significant coagulation dysfunction or bleeding, it is likely that a significant hematoma will form behind the patient’s vertebroplasty spine, resulting in a hematoma and the risk of hematoma infection; 5, the patient’s target vertebra has osteomyelitis, which is not recommended for vertebroplasty surgery and is an absolute contraindication; 6, the patient is allergic to any items required for surgery: the patient is allergic to bone cement or patients with high reactivity status are also not recommended for vertebroplasty surgery; relative contraindication, patients with vertebral fracture and compression of nerve roots, and the compression symptoms are not due to vertebral instability, but are intractable pain, patients are not recommended for vertebroplasty surgery. Simply put, the radicular pain significantly exceeds the vertebral body pain, and the pain is caused by compression symptoms unrelated to vertebral body collapse; performing vertebroplasty surgery is mainly to relieve the pain caused by the patient’s vertebral body fracture, but there is no obvious repositioning effect on the compression in the spinal canal, so the fracture block recession causes obvious spinal canal compression is also not recommended to perform vertebroplasty surgery; severe vertebral body collapse, the degree of collapse is very low patient vertebroplasty The vertebroplasty procedure cannot guarantee complete or better correction of the patient’s vertebral height; painless, stable fractures with a long disease duration beyond the period of fracture healing; three or more segments treated simultaneously at one time is a relative contraindication, because a large number of segments treated simultaneously at one time may increase the risk of intraoperative thrombosis or pulmonary infarction in patients, and is also a relative contraindication.