Petechiae on the conjunctiva are one of the clinical manifestations of sepsis. The clinical onset of sepsis is rapid, and the rash takes the form of petechiae, urticaria, pustular rash, and scarlet fever-like rash with petechiae on the conjunctiva. Gram-negative coccus sepsis can cause petechiae on the conjunctiva. The examination of petechiae on the conjunctiva caused by sepsis in the elderly: 1. Blood test: The total blood cell count increases, usually in the range of (10-30) × 109/L, the percentage of neutrophils increases, there may be a significant nuclear left shift and intracellular neutrophil granules, and eosinophils decrease or disappear. The total leukocyte count may be normal or low in those with poor organism reactivity and in a few patients with gram-negative bacillary sepsis, but the neutrophil count is still increased. 2, pathogenic examination: blood culture is the most important, should be performed before the application of antibacterial drugs and chills, high fever, and should be repeatedly sent to the test, each collection of blood volume of 5ml for newborns and infants, 10ml for older children and adults. 3, C-reactive protein measurement: after the bacterial infection, C-reactive protein 6 to 8 hours will rise, when the infection is controlled can be reduced within a short period of time, so it also helps to observe the efficacy and Prognosis judgment. 4.Peripheral blood routine: the total number of white blood cells is increased or decreased, the proportion of rod-shaped nucleated cells in neutrophils is increased, and the platelet count is increased. Other tests: The horseshoe crab lysate test (LLT) can detect the endotoxin of gram-negative bacilli in serum and other specimens, but it cannot identify the pathogenic bacteria, which is helpful for the diagnosis of gram-negative sepsis. If there is damage to the heart, liver, kidneys and other organs during the course of the disease, or in case of shock or DIC, corresponding tests should be performed.