The dangers of non-shedding endometrium may cause endometrial thickening, endometrial polyps, endometrial neoplasia-like hyperplasia, and in serious cases, endometrial cancer. The most common clinical cause of endometrial non-exfoliation is ovarian dysfunction, which causes poor endometrial shedding. Normal endometrial exfoliation is under the influence of ovarian hormones, estrogen makes endometrial proliferation and progesterone makes endometrial exfoliation. If the hormone level is disturbed, it may affect the excessive growth of endometrium, and without the effect of progesterone, the endometrium cannot be exfoliated well, which will lead to thickening of endometrium and continuous bleeding from vagina, which may cause a lot of bleeding and serious blood loss anemia, and also the risk of endometrial cancer due to excessive thickening of endometrium. Therefore, if the endometrium does not shed, it is recommended to go to the hospital for appropriate examination and treatment as soon as possible.