After depression is cured, there is still a possibility of relapse. Clinical studies have found that after regular, scientific and standardized treatment of first-episode depression, half of the patients still experience relapse within the next five years while taking medication. Patients with first-episode depression who improve after treatment can have a recurrence rate of depression of up to 80% after one year if they stop taking medication. Depression is a disease with a high cure rate and a high relapse rate; therefore, in the clinical treatment of depression, it is generally recommended that the first treatment of depression should be adhered to for a period of time. Some clinical guidelines suggest that adherence to medication for one year after depression is cured can significantly improve the recurrence of depression. In the corresponding literature, it is found that depressed patients have seven chances of relapse in their lifetime, so depressed patients should actively stay alert and do the corresponding, scientific and standardized treatment, such as medication, psychotherapy, physical therapy, etc. In the process of seasonal changes there are changes in the condition, and timely use of the corresponding treatment can improve or have a very important role in the improvement of depression and can play a certain role in slowing down the relapse of depression.