Colds are usually caused by viral infections. Cold chills may be a pre-febrile reaction to chills, which can be treated symptomatically with antipyretic and analgesic medications such as ibuprofen, and antiviral treatment can be given if necessary. Antiviral treatment can be given if necessary. Antibiotics can be used if there is a secondary bacterial infection. Both common cold and influenza can cause fever and chills. For chills caused by the common cold, symptomatic treatment with antipyretic drugs such as ibuprofen and acetaminophen may be indicated, and antiviral treatment is not usually necessary. If fever and chills are caused by influenza, antiviral medications such as oseltamivir should be used early in the course of treatment in addition to symptomatic treatment. Colds with secondary bacterial infections may lead to worsening of symptoms, such as elevated temperature, coughing up yellow sputum and runny nose, etc. Antibiotics such as amoxicillin and cefixime can be used to fight infections, and antibiotics can be adjusted according to the results of drug sensitivity, if necessary. Chills can also be caused by other diseases, if the symptoms do not improve or aggravate, it is recommended to consult a doctor in a timely manner, under the guidance of reasonable and standardized treatment.