Fluoxetine and aripiprazole can generally be taken together, fluoxetine and aripiprazole taken together for the treatment of depression, there is generally no drug interaction, but because of their similar effects, need to comply with the doctor’s advice to reduce the dose accordingly. Fluoxetine is used in the treatment of depressive mental disorders such as mild or major depression, bipolar affective disorder, psychogenic depression and depressive neurosis, obsessive-compulsive disorder and other diseases. The dosage requirements for the treatment of different disorders are different and must be used under the supervision of a doctor. It is contraindicated in patients who are allergic to fluoxetine and should not be taken together with monoamine oxidase inhibitors. Aripiprazole is used for the treatment of schizophrenia and psychotic symptoms such as manic episodes, bipolar disorder, and Tourette’s syndrome in children. Adverse reactions such as edema and chest pain, anorexia, nausea and vomiting may occur after administration. It is not recommended for use in pregnant women, nursing women need to stop breastfeeding to take the drug, and is not recommended for patients under 18 years of age. If you need to use fluoxetine and aripiprazole, need to follow the doctor’s instructions. If discomfort occurs during co-taking, patients are advised to go to the hospital in time.