Macrophthalmia, medically known as blepharitis, is an acute inflammatory condition that develops when purulent bacteria, such as Staphylococcus aureus, invade the eyelid glands. Blepharitis usually presents as redness, swelling, heat, and pain in the affected area, and on palpation can be found as a nodule with subcutaneous pressure, hard texture, and more intense pain. The treatment of blepharitis requires the use of antibiotic medications and incision and drainage.1. Antibiotic medications: In early stages of infection, when redness, swelling, heat and pain are evident, antibiotics such as amoxicillin and azithromycin can be applied as prescribed by the doctor, avoiding local hot compresses to prevent aggravation of local bacterial growth. At the same time, use antibiotic eye drops, such as levofloxacin eye drops, tobramycin eye drops and other anti-infection treatments. Do not squeeze the abscess before it is formed, otherwise it will lead to the spread of inflammation and cellulitis of the eyelid, and bacteria will enter the brain through the cavernous sinus, which may also cause bacterial meningitis, sepsis and other life-threatening conditions; 2. Incision and drainage: the abscess should be incised after it is formed to drain the pus and speed up recovery. When the abscess is large, drainage strips should also be placed to promote the discharge of pus. At this time, oral antibiotics such as azithromycin and cefaclor should also be taken as prescribed by the doctor to control the infection. During this period, the condition should be closely observed for early detection of changes in the condition, avoid rubbing the eyes with hands, and try to keep the lesion area dry to avoid aggravating the infection.