Usually it is not abdominal pain that causes diarrhea, but abdominal pain and diarrhea occur together, which may be physiological causes or pathological causes such as gastric diseases, intestinal diseases, hepatobiliary and pancreatic diseases, endocrine system diseases, acute poisoning and so on. 1. Physiological causes: (1) Environment: if the weather suddenly becomes cool or hot, if the weather suddenly becomes cool, so that the abdomen is cold, it will lead to accelerated intestinal peristalsis and inadequate absorption; if the weather is too hot, it will make the digestive juices secretion is insufficient, causing intestinal dyspepsia, and change the appearance of abdominal pain, diarrhea symptoms. (2) Lifestyle: such as not paying attention to dietary hygiene, overeating, alcoholism, spicy and other stimulating foods, these bad habits can also cause abdominal pain with diarrhea. 2. Pathologic causes: (1) Stomach diseases: such as chronic atrophic gastritis, gastric ulcer, gastric cancer and so on. (2) Intestinal diseases: infectious enteritis caused by rotavirus or adenovirus, dysentery, etc., as well as Crohn’s disease, ulcerative colitis, intestinal polyps, irritable bowel syndrome and so on. (3) Hepatobiliary and pancreatic diseases: such as gallstones, cholecystitis, pancreatitis, hepatocellular carcinoma, pancreatic cancer and so on. (4) Endocrine system diseases: such as hypoadrenocorticism, hyperthyroidism and so on. (5) Acute poisoning: such as poisoning caused by accidental ingestion of puffer fish, poisonous mushrooms, tung oil and chemical substances such as arsenic, lead, phosphorus and mercury. Abdominal pain and diarrhea can occur at the same time, if abdominal pain with diarrhea to exclude physiological causes, should be timely to the hospital, identify the cause of the disease, the cause of treatment.