The treatment of blackheads all over the lips includes topical medication, oral medication, physical therapy, and other auxiliary treatments. 1. Topical medication: patients with blackheads all over their lips can generally be given a coating of retinoic acid cream, adapalene gel, etc. to remove blackheads. 2. Oral medication: Oral retinoic acid preparations such as isotretinoin, antibiotics such as minocycline and other medications can be taken. 3. Physical therapy: If medication is not effective, then acid peels can be given to get rid of blackheads. Or use cosmetic lasers. 4. Other auxiliary treatment: If the lips blackheads more, then you can give acne squeezer to squeeze out the contents of the treatment. Finally, the phenomenon of blackheads all over the upper and lower lips, please consult a doctor in time, the above drugs must follow the doctor’s instructions.