The concept of pulsed radiofrequency was introduced by Sluijter in 1997. In 1999, Munglani used pulsed radiofrequency at the spinal nerve roots and dorsal root ganglia to treat four patients with intractable neuropathic pain and achieved more than 90% pain relief, and the efficacy was maintained at seven months follow-up. The real exposure to pulsed radiofrequency technology in China was introduced in September 1999 by Dr. Goss from London, England, who came to Guangzhou to give lectures. Compared with the traditional RF method, the main advantage of pulsed RF is that it uses 20 ms/sec pulsed current, its control voltage is <40v, its controllable temperature is <42℃, and according to the current research data, it will not damage the nerve fibers when the temperature is <45℃, so if we use this technology in the process of analgesia, we don't need to worry about damaging the nerve roots, thus its use range will be bigger and safer than the existing Therefore, it can be used in a larger and safer way than the existing radiofrequency treatment. The greatest advantage of pulsed radiofrequency is that electrical stimulation of the nervous system has a neuro-modulation effect rather than a destructive effect. This satisfies the goal of modern pain medicine to treat pain by modulating nerve function without damaging nerve tissue. While the traditional view is that RF current causes nerve damage through heat generation, Kleef and Slappendel's study concluded that it is the RF current, not the heat, that is responsible for the effect. Main mechanisms of action: 1, inhibition of nerve fiber impulse conduction or electrophysiological activity processes; 2, plasticity changes in pain information transmission and processing pathways; 3, activation of the spinal pain sensory inhibition system; 4, modulation of pain mediator levels in the central nervous system. The main advantages: 1, through the regulation of nerve function to achieve the treatment of pain; 2, is a minimally invasive treatment and does not damage the nerve, selective, treatment safety factor is high; 3, repeatable treatment, less complications; 4, the operation of accurate positioning; problems: 1, the best treatment interval to be further studied; 2, consolidation of treatment time. Pulsed radiofrequency neuromodulation is currently considered to be the most promising new technology. Pain disorders that can achieve effective treatment clinically include: intractable post-herpetic neuralgia, chronic post-surgical neuralgia, post-operative disc pain, trigeminal neuralgia, post-abortion abdominal pain and diabetic foot.