Black pigmentation under the nose may be caused by post-inflammatory hyperpigmentation, melanosis, or hereditary factors, which can be eliminated by medication and laser treatment. 1. Post-inflammatory hyperpigmentation: Melanin can be lightened by applying topical medications such as sodium heparin gel, hydroquinone cream and vitamin E cream. 2. Melanosis: after stopping exposure to disease-causing factors, topical hydroquinone cream, deoxyarbutin, or combined oral vitamin C, tranexamic acid and other drugs can be used. 3. Hereditary factors: such as coffee spots, can be broken up by laser melanin particles under the nose, so that with the metabolism out of the body, to achieve the purpose of eliminating melanin deposits, pay attention to the postoperative good sunscreen. Melanin deposits under the nose, generally have no effect on normal life, if you are more concerned, you can go to the dermatology department to choose the appropriate treatment to improve, to avoid the adverse consequences of self-medication. The medication should be used in accordance with the doctor’s instructions.